Comprehensive Study of Nirgundi Plant: A Survey Report
DOI:
https://doi.org/10.56511/JIPBS.2015.v2.i02.pp125-130Abstract
The genus Vitex contains 270 species distributed around the world. It is an interesting source of potential bioactive molecules, as iridoids compounds, flavonoids, diterpenoids derivatives, phytosteroids, with antioxidant, anti-inflammatory, antimicrobial, Hepatoprotective activity, analgesic and antihistamine. It is a large aromatic shrub distributed throughout India. In ancient times it is used as a female remedy and also for pains in Ayurveda and also in Roman medicine. It is distributed through Indo-Malesia, Europe, Asia, West Indies and india, in india it is found in the outer Himalayas. It is also called as village pharmacy because it is used for the many disease like antibacterial, astringent, febrifuge, vermifuge, sedative, antitumor, tonic various chemical constituents like flavones, glycosides, volatile oil, flavonoids, tri terpenes, and tannins many others were identified in this plant.
Keywords:
Nirgundi, Antibacterial Activity, Anticulscunt ActivityDownloads
References
Adnaik RS, Pai PT, Mule SN, Naikwade NS, Magdum CS. Laxative Activity of Vitex negundo Linn. Leaves. Asian J. Exp. Sci. 2008; 22(1): 159-160.
International journal of advances in pharmacy,Biology and chemistry Vol. 1(1), JanMar, 2012, Natural product redience vol 4(3) may-june 2005
Liu C, Tseng A, Yang S. Chinese herbal medicine: modern applications of traditional formulas. Florida, USA: CRC Press; 2005.
Zheng CJ, Zhao XX, Ai HW, Lin B, Han T, Jiang YP, et al. Therapeutic effects of standardized Vitex negundo seeds extract on complete Freund’s adjuva nt induced arthritis in rats. Phytomedine 2014; 21: 838-846.
Vinuchakkaravarthy T, Kumaravel KP, Ravichandran S, Velmurugan D. Active compound from the leaves of Vitex negundo L. shows anti-inflammatory activity with evidence of inhibition for secretory phospholipase A2 through molecular docking. Bioinformation 2011; 7: 199-206.
Chattopadhyay P, Hazarika S, Dhiman S, Upadhyay A, Pandey A, Karmakar S, et al. Vitex negundo inhibits cyclooxygenase-2 inflammatory cytokine-mediated inflammation on carrageenan-induced rat hind paw edema. Pharmacogn Res 2012; 4: 134-137.
Baytop T. Therapy with Medicinal Plants (Past and Present) I, Stanbul University Publications, Istanbul, 1984, pp. 252.
Honda G, Yes ilada, Tabata M, Sezik E, Fujita T, Takeda Y, Takaishi Y, Tanaka T. Traditional medicine in Turkey VI. Folk medicine in West Anatolia: Afyon, Kutahya, Denizli, Mugla, Aydın provinces. Journal of Ethnopharmacology 1996; 53: 75-87.
Gomaa CS, El-Mokhazy MA, Halim FA, ElSayyad AE. Flavonoids and iridoids from Vitex agnus-castus . Planta Medica 1978; 33: 277.
Sirait M, Rimpler H, Ha nsel R. Flavonoide aus Vitex agnus castus L. Experientia 1962; 18: 72.
Wollenweber E, Mann K. Flavonols from fruits of Vitex agnus-castus . Planta Medica 1983; 47:126-127.
Hoberg E, Meier B, Sticher O. Quantitative high performance liquid chromatographic analysis of casticin in the fruits of Vitex agnus-castus. Pharmaceutical Biology 2001; 39: 57-61.
Hoberg E, Orjala J, Meier B, Sticher O. Diterpenoids from the fruits of Vitex agnus-castus. Phytochemistry 1999; 52: 1555-1558.
Sorensen JM, Katsiotis ST. Parameters influencing the yield and composition of the essential oil from Cretan Vitex agnuscastus fruits. Planta Medica 2000; 66: 245250.
Saden-Krehula M, Kustrak D, Blazevic N. 43-Ketosteroids in flowers and leaves of Vitex agnus-castus . PlantaMedica 1990; 56: 547.
Alam MI, Gomes A. Snake venom neutralization by Indian medicinal plants ( Vitex negundo and Emblica officinalis ) root extracts. Journal of Ethnopharmacology 2003, 86: 75-80.
Karunamoorth K, Ramanujam S, Rathinasamy R. Evaluation of leaf extracts of Vitex negundo L. against larvae of Culex tritaeniorhynchus and repellent activity on adult vector mosquitoes. Parasitol Res. 2008; 103: 545 – 550.
Adnaik RS, Pai PT. Laxative activity of vitex negundo linn. Leaves, Asian J. Exp. Sci. 2008; 22(1): 159-160.
Rastogi T, Bhutda V, Moon K, Aswar PB, Khadabadi SS. Comparative Studies on Anthelmintic Activity of Moringa Oleifera and Vitex . Asian J. Research Che. 2009; 2(2): 217-221
Chandramu C, Manohar RD, Krupadanam DGL, Dashavantha RV Isolation characterization and biological activity of betulinic acid and ursolic acid from Vitex negundo L. Phytother. Res. 2003; 17:129134.
Chawla AS, Sharma AK, Handa SS. Chemical investigation and anti inflammatory activity of Vitex negundo seeds. Part I. Indian J. Chem. 1991; 30B: 773 – 776.
Mukherjee KS, Badruddoza S. Chemical constituents of Dillenia indica Linn. And Vitex negundo Linn. J. Indian Chem. Soc. 1981; 58:97.
Maurya R, Shukla PK, Ashok K . New antifungal flavonoid glycoside from vitex negundo. Bioorganic and Medicinal Chemistry 2007; 17:239-242.
Gautam LN. Chemical constituents from vitex negundo (Linn.) of nepalese origin. Scientific World 2008; 6: 6.
Khan MSS, Syeed HS, Haneefuddin M, Akter L, Asmatullah M, Jahan S, et al. Screening and evaluation of antioxidant, antimicrobial, cytotoxic, thrombolytic and membrane stabilizing properties of the methanolic extract and solventsolvent partitioning effect of Vitex negundo bark. Asian Pac J Trop Dis 2013; 3: 393-400.
Nagarsekar KS, Nagarsenker S, Kulkarni R. Antioxidant and antilipid peroxidation potential of supercritical fluid extract and ethanol extract leaves of Vitex negundo Linn. Indian J Pharm Sci 2011; 73: 422429.
Devi PR, Kumari K, Kokilavani C, Effect of Vitex negundo leaf extract on the free radicals scavengers in complete freund’s adjuvant induced arthritic rats. Indian Journal of Clinical Biochemistry. 2007; 22 (1): 143-147.
Tandon VR, Gupta RK, Vitex negundo Linn (VN) leaf extract as an adjuvant therapy to standard anti-inflammatory drugs. Indian J Med Res. 2006; 124(4): 447-50
Bansod MS, Harle UN, Vitex negundo L: Phytochemical constituents, traditional uses and pharmacological properties: Comprehensive review. Pharmacologyonline Newsletter. 2009; 1: 286-302.
Jabeen, A., Khan, M., Zafar, M. and Ahmad, F. (2009) ‘Indigenous uses of economically important flora of Margallah Hills National Park, Islamabad, Pakistan’, African Journal of Biotechnology. 8, 763‐784.
Vishwanathan, A. S., Basavaraju, R. (2010) ‘A Review on vitex negundo L.‐A medicinally important plant’, EJBS. 3(1), 30‐42.
Published
How to Cite
Issue
Section
Copyright (c) 2015 Rakesh Tiwle, D. K. Sanghi
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Journal of Innovations in Pharmaceutical and Biological Sciences is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. Based on a work at