In vitro hemostatic activity of ethanol extracts of Beetroot (Beta vulgaris L.) in blood male albino rat
Abstract
Objective: The purpose of this research was to determine the in vitro hemostatic activity of ethanol extract of beetroot (Beta vulgaris L). Methods: In vitro hemostatic activity was performed on whole blood of rat by Lee-White method to determine the clotting time and the Eustrek method to observe the microscopic picture of clotted blood. Results: The results of in vitro study showed that ethanol extract of Beetroot at the concentration of 1% and 2% decreased the clotting time at the minute of 24.4+1.14 and 15.9 + 0.65, respectively, as compared to EDTA treatment which did not clot for 120 min (p<0.05) and microscopically showed that blood cells appear to be attached to each other at the concentration of 1% and 2% of ethanol extract of Beetroot. The hemostatic activity of ethanol extract of beetroot showed a dose-dependent manner in the in vitro study. Conclusion: Ethanol extract of beetroot (Beta vulgaris L) has hemostatic activity on in vitro method.
Keywords:
Beetroot (Beta vulgaris L.), Hemostatic, Lee-white, EustrekDownloads
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Copyright (c) 2018 Sony Eka Nugraha, Edy Suwarso, Yuandani
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