Novel synthetic and commercial oriented synthesis of substituted benzofuran moiety

Authors

  • P Ayash Kumar Analytical Research Department, TEVA API India Limited, Greater Noida-201308; U.P., India
  • Sradhanjali Mohapatra PDM College of Pharmacy, Bahadurgarh, Haryana, India
  • Sanjita Das Department of Pharmacy, Noida Institute of Engineering and Technology, Greater Noida, U.P., India
  • Saumya Priya Basu Department of Pharmacy, Noida Institute of Engineering and Technology, Greater Noida, U.P., India

Abstract

Substituted benzofuran moiety i.e. Pongamol the target nucleus is reported to having various biological activity like anti-convulsant, sedative (prologation of sleeping time), anti oxidant and dislipidemic etc. due to structural correlation to CNS acting drugs. All the available data of Pongamol were based from natural or semisynthetic source. This encourages going for a synthesis of Pongamol with industrial friendly process. Pongamol is prepared synthetically using easily available source and quick, cost effective and high yielding process.

 

Keywords:

Pongamol, Substituted benzofuran moiety, retention time (RT), reflux, semisynthetic, industrial friendly process

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Published

05-10-2016
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How to Cite

P Ayash Kumar, Sradhanjali Mohapatra, Sanjita Das, and S. P. Basu. “Novel Synthetic and Commercial Oriented Synthesis of Substituted Benzofuran Moiety”. Journal of Innovations in Pharmaceutical and Biological Sciences, vol. 3, no. 4, Oct. 2016, pp. 116-20, https://jipbs.com/index.php/journal/article/view/197.

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Research Article