Pharmacognostical and Physico-Chemical Standardization of Triphala Guggulu Vati: An official Ayurvedic Formulation
DOI:
https://doi.org/10.56511/JIPBS.2015.v2.i04.pp439-451Abstract
Ayurveda is considered as the “science of life,” because the ancient Indian system of health care focused views of man and his illness. India has an age old heritage of traditional herbal medicine. Herbal drugs are being preferred to synthetic antibiotics. Triphala-guggulu vati is official in Ayurvedic Formulary of India and is prescribed for the treatment of cough and fever. Currently, Triphala is being extensively researched for its various therapeutic effects including its anti-caries, antioxidant, anti-collagenase, and anti‑microbial activities. It is a polyherbal preparation containing five ingredients. In this research paper, an attempt has been made to develop standardization methods for some of the ingredients of Triphala-guggulu vati. A standard laboratory reference sample of Triphala-guggulu vati and two marketed samples were evaluated as per the developed method. All the formulations were standardized on the basis of organoleptic, physical characteristic, physico chemical properties and various pharmacognostical parameters. The standardization study shows that the commercial formulation matches with the authentic standards as per WHO guidelines. The inference from this study can be used as reference standard in further quality control researches.
Keywords:
Triphala-guggulu vati, Ayurvedic official formulation, standardization, WHO guidelinesDownloads
References
Quality assurance of Pharmaceuticals - guidelines and related materials: Good manufacturing practices and Inspection. 2nd ed. Geneva: World Health Organization; 2007.
Tambekar D.H., Dahikar S.B., Lahare M.D., Antibacterial potentials of some herbal preparations available in India. Res J Med Med Sci 2009; 4:224; 7.
Chattopadhyay R.R., Bhattacharyya S.K., Terminalia chebula: An update. Pharmacogn Rev 2007; 1:151;6
Bhutani, K.K., Eastern Pharmacist, 2000, 43, 21
Xie Z., Chaudhary R.R., Rafei U.M., Harmonization of traditional and modern medicine. Traditional Medicine in Asia. New Delhi: World Health Organization, Regional Office for South -East Asia: 2002. p. 115-34.
Ayurvedic Formulary of India, Part I. Government of India, Ministry of Health and Family welfare. New Delhi: Department of Health, Controller of Publications; 1989. p. 154.
Ayurvedic Formulary of India, Part II, Volume II, Government of India, Ministry of Health and Family welfare. New Delhi: Department of Health, Controller of Publications; 1989. p. 189-191.
Chopra RN, Nayar SL, Chopra IC. Glossary of Indian Medicinal Plants. 2nd ed. New Delhi: Publication and Information Directorate, CSIR; 1999, 75, 106, 194, 241,242.
The Indian Herbal Pharmacopoeia. New Delhi: A Joint Publication of Regional Research Laboratory, Indian Drug Manufacturers Association; 1998, 93, 50, 162.
Kirtikar K.R., Basu B.D., Indian Medicinal nd Plants. 2 ed. Delhi: Sri Satguru Publications; 2006.
The Wealth of India. A Dictionary of Indian Raw Materials and Industrial Products. New Delhi:National Institute of Science and Communication (C.I.S.R.); 1998, 34, 96, 164, 171.
Ayurvedic Formulary of India, Part II, Volume II, Government of India, Ministry of Health and Family welfare. New Delhi: Department of Health, Controller of Publications; 1989. p. 189.
Wallis T. E., Text Book of Pharmacognosy, th
Edition, London; J A Churchill Ltd; 1967:6
Ayurvedic Formulary of India, Part II, Volume II, Government of India, Ministry of Health and Family welfare. New Delhi: Department of Health, Controller of Publications; 1989. p. 190.
Sinko P J. Martin’s Physical Pharmacy and th Pharmaceutical Sciences. 5 Indian. B I Publication Pvt. Ltd. 2006: 555. Edition
Subramanyam C.V.S., Text book of Physical Pharmacy, Second Edition, Reprint 2010, Micromeritics, 180-230.
Gibson M., Pharmaceutical Preformulation and Formulation. A practical Guide from Candidate Drug Selection to commercial Dosage form. Boca Raton: CRC press. ISBN 1-57491-120-1.
Government of India, Ministry of health and Family Welfare, Department of I.S.M. & H. Anonymous, The Ayurvedic Pharmacopoeia of India. 1st Edition, New Delhi: 1999, Part I Volume – IV.
World Health Organization (WHO), Quality Control Methods for Medicinal Plants Materials, Geneva 1988:1-115.
Iyengar M.A., Pharmacognosy of powdered crude Drugs. Manipal Power Press, Manipal, First Edition. 1980: 1-4
Kaymak H.C., Guvenc I. and Gurol., A: Elemental analysis of different Radish (Raphanus sativus L.) cultivars by using wavelength-dispersive X-ray fluorescence spectrometry. Bulgarian Journal of Agricultural Science 2010, 16(6): 769-777.
Mohapatra P., Shirwaikar A. and Aswatha Ram H.N., “Standardization of a polyherbal formu lation”, Pharmacognosy magazine, 2008, V-4 I -13, 65-69.
Kokate C. K., Practical Pharmacognosy, New Delhi: Vallabh Prakashan; 1994:107113.
Indian Pharmacopoeia. The controller of publication, New Delhi; Ministry of health and family welfare. India; 1996, 2:736.
Indian Pharmacopoeia. The controller of publication, New Delhi; Ministry of health and family welfare. India. 5th ed. 2007. Volume I and II.
Indian Pharmacopoeia. The controller of publication, New Delhi; Ministry of health and family welfare, Appendix. 7.1; A-80, New Delhi; Controller of Publication, 1996, P. No. 2.
Indian Pharmacopoeia. The controller of publication, New Delhi; Ministry of health and family welfare, Appendix. 7.1; A-80, New Delhi; Controller of Publication, 1996, P. No. 2-3.
Indian Pharmacopoeia. The controller of publication, New Delhi; Ministry of health and family welfare. India; 1996, 2:734.
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