Liver diseases and herbal drugs:-A review

Abstract

Liver is a vital organ play a major role in metabolism and excretion of xenobiotics from the body. Liver cell injury is generally caused by various toxic chemicals (certain anti-biotic, chemotherapeutic agents, carbon tetrachloride (CCl₄), thioacetamide (TAA) etc.), excessive alcohol consumption and microbes is well-studied. The available synthetic drugs to treat liver disorders in this condition also cause further damage to the liver. Hence, Herbal drugs have become increasingly popular and their use is wide-spread. Herbal medicines have been used in the treatment of liver diseases for a long time so the maintenance of a healthy liver is get possible. The main reason for Liver injury is the toxins produced by our body metabolites. Herbal remedies are focused to give safe route for reliving liver disorders. Therefore, hepatoprotective natural products such as Andrographis paniculata, Silymarine Pirorrhiza, Punarnava, Liquorcie, Azadirachta indica, Curcuma longa, Eclipta alba, Fumaria officinalis, Phyllanthus amarus, Phyllanthus niruri, Phyllanthus embellica , Solanum nigrum, Tinospora cordifolia, Uncaria gambir, Withania somnifera, Swertia chirata, Camellia sinensis, Ginkgo biloba. Linn is reviewed. The present review is aimed at compiling data on promising phytochemical from medicinal plants that have been tested in hepatotoxicity models using modern scientific system.