A parallel arm interventional clinical Study to assess the efficacy and tolerability of ointment with natural ingredient in patients with chronic osteoarthritis of knee and low back ache

Abstract

Background: Treatment of OA focuses on reducing symptoms. Such treatment can be analgesic or nonsteroidal anti-inflammatory agents. With the current frequency and severity of adverse effects from analgesics and NSAIDs, suggestions for safer and sustainable interventions to manage the pain and stiffness are warranted. Natural local remedies, because of their relative safety, may reduce dependency on NSAIDs and analgesics and could have an important role in the treatment of OA. Trial design: Trial was parallel arm involving 60 patients with chronic osteoarthritis of knee and low back ache included in two parallel groups, Treatment Group (AVI- TR 01), and Control Group (n = 30/group). Methodology: The study involved assessment of changes in pain score with VAS, changes in WOMAC score, changes in severity of other symptoms like swelling, tenderness between treatment and control groups for the period of 14 days.  Results and conclusion: It can be concluded that AVI- TR 01 treatment for pain and stiffness in patients with osteoarthritis by proving relief from pain, swelling, stiffness etc. It led to improvement in quality of life for the patients. There was reduction in the requirement of oral analgesics for the subjects using regular AVI- TR 01 for 14 days. Thus it can be concluded from the present study that the treatment with AVI- TR 01 is safe and effective solution to manage pain and stiffness in osteoarthritis