Comparative Systematic Review and Efficacy of Various Vaccines Against SARS-COV-2
DOI:
https://doi.org/10.56511/JIPBS.2021.v8.i04.pp01-13Abstract
This review article is based on the current scenario wherein COVID-19 is dominating the world. COVID-19 has caused losses of innumerable lives while the battle to eradicate the virus is still on. The main weapon to help us overcome this pandemic is the vaccines provided to us by the research scientists. More than twelve vaccines have been introduced in the market having safety and efficacy. These vaccines will help us reduce the number of cases emerging every day and help us sustain through these difficult times. The article aims to compare and evaluate different vaccines available in the market. The vaccines compared are Covishield, Covaxin, Pfizer BioNTech, Moderna, Novavax, Janssen, Sputnik V, EpiVacCorona, CoviVac, Sino pharm, Sinovac, CanSinoBio and RBD-dimer. The review article also covers the calculation related to the efficacy of the vaccines.
Keywords:
Covid-19, Vaccine, Virus, Infection, PandemicDownloads
References
Coronavirus disease 2019 (COVID-19) - Prognosis | BMJ Best Practice US.
Pathophysiology, Transmission, Diagnosis, and Treatment of Coronavirus Disease 2019 (COVID-19): A Review | Critical Care Medicine | JAMA | JAMA Network.
Genomic epidemiology of superspreading events in Austria reveals mutational dynamics and transmission properties of SARS-CoV-2 | Science Translational Medicine (sciencemag.org).
Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study - The Lancet Infectious Diseases.
Harrison AG, Lin T, Wang P. Mechanisms of SARS-CoV-2 transmission and pathogenesis. Trends in immunology. 2020 Oct 14.
Lalchhandama K. The chronicles of coronaviruses: the bronchitis, the hepatitis and the common cold. Science Vision. 2020; 1:43-53.
https://en.wikipedia.org/wiki/COVID-19.
https://en.wikipedia.org/wiki/File:Fphar-11-00937-g001.jpg.
Verdecchia P, Cavallini C, Spanevello A, Angeli F. The pivotal link between ACE2 deficiency and SARS-CoV-2 infection. European journal of internal medicine. 2020; 76:1420.
www.who.int.Coronavirus disease (COVID-19): How is it transmitted? Available from: https://www.who.int/newsroom/q-a-detail/coronavirus-disease-covid-19-how-is-ittransmitted.
www.who.int. How do vaccines work? Available from: https://www.who.int/news-room/feature-stories/detail/how-dovaccines-work.
World Health Organization. WHO position on HPV vaccines. Vaccine. 2009; 27(52):7236-7.
Healthline.com. Everything You Need to Know About Vaccinations. Available from: https://www.healthline.com/health/vaccinations
Wikipedia.org.Vaccine. Available from: https://en.wikipedia.org/wiki/Vaccine.
Wikipedia.org. COVID-19_vaccine. Available from:.https://en.m.wikipedia.org/wiki/COVID-19_vaccine.
www.gavi.org. What are whole virus vaccines and how could they be used against COVID-19? Available from: https://www.gavi.org/vaccineswork/what-are-whole-virusvaccines-and-how-could-they-be-used-against-covid-19.
www.gavi.org. What are whole virus vaccines and how could they be used against COVID-19? Available from: https://www.gavi.org/vaccineswork/what-are-whole-virusvaccines-and-how-could-they-be-used-against-covid-19.
cglife.com.mrnna-vaccines-what-you-need-to-know. Available from:https://cglife.com/blog/mrna-vaccines-what-you-need-toknow/
theconversation.com. From adenoviruses to RNA: the pros and cons of different COVID vaccine technologies Available from: https://theconversation.com/from-adenoviruses-to-rna-thepros-and-cons-of-different-covid-vaccine-technologies
https://www.google.com/amp/s/www.researchgate.net/figure/ Advantages-and-disadvantages-of-major-viralvectors_tbl1_281623861/amp
towardsdatascience.com. pfizer and moderna vaccine efficacy calculated from data. Available form: https://towardsdatascience.com/pfizer-and-moderna-vaccineefficacy-calculated-from-data-9566897173c
sputnikvaccine.com. The sputnik v vaccine‟s efficacy is confirmed at 91.4% based on data analysis of the final control point of clinical trials. Available from:https://sputnikvaccine.com/newsroom/pressreleases/thesputnik-v-vaccine-s-efficacy-is-confirmed-at-91-4-based-ondata-analysis-of-the-final-control-po/
www.news18. bharat-biotechs covaxin has 81% efficacy heres how it compares to serum institutes covishield com . Available from https://www.news18.com/amp/news/india/bharatbiotechs-covaxin-has-81-efficacy-heres-how-it-compares-toserum-institutes-covishield-3496130.html
https://www.novavax.com/sites/default/files/202011/2019nCo V302Phase3UKVersion2FinalCleanRedacted.pdf
www.raps.org. covid 19vaccine tracker. Available from. https://www.raps.org/news-and-articles/newsarticles/2020/3/covid-19-vaccine-tracker
nytimes.com. covid 19vaccine tracker . Available from: .https://www.nytimes.com/interactive/2020/science/coronaviru s-vaccine-tracker.html
www.seruminstitute.com . Available from:.https://www.seruminstitute.com/pdf/covishield_fact_she et.pdf
https://www.facebook.com/lapipette.labs/?ref=py_c
www.bharatbiotech.com.Available from: https://www.bharatbiotech.com/images/covaxin/covaxin-factsheet.pdf
www.cdc.gov.Availbale from:https://www.cdc.gov/coronavirus/2019ncov/vaccines/different-vaccines/Pfizer-BioNTech.html
www.fda.gov.emergency preparedness and response coronavirus disease. .Available from: https://www.fda.gov/emergency-preparedness-andresponse/coronavirus-disease-2019-covid-19/pfizer-biontechcovid-19-vaccine
www.cdc.gov.Availabe from:https://www.cdc.gov/vaccines/covid-19/info-byproduct/clinical-considerations.html
www.cdc.gov. Available from:https://www.cdc.gov/coronavirus/2019ncov/vaccines/different-vaccines/Moderna.html
www.ema.europa.eu. Available from: https://www.ema.europa.eu/en/documents/productinformation/covid-19-vaccine-moderna-epar-productinformation_en.pdf
www.cdc.gov.Available from:https://www.cdc.gov/vaccines/covid-19/info-byproduct/moderna/index.html
wikipedia.org. Available from:https://en.wikipedia.org/wiki/EpiVacCorona
www.precisionvaccinations.Avaible from:https://www.precisionvaccinations.com/vaccines/epivacc orona-vaccine
www.precisionvaccinations.com. Available from:https://www.precisionvaccinations.com/vaccines/covivac -russia-covid-19-vaccine
wikipedia.org. Available from:https://en.wikipedia.org/wiki/CoviVac
www.bbc.com. Covid: What do we know about China's coronavirus vaccines?. Available from. https://www.bbc.com/news/world-asia-china-55212787
wikipedia.org. Available from. https://en.wikipedia.org/wiki/BBIBP-CorV
wikipedia.org. Available from: https://en.wikipedia.org/wiki/CanSino_Biologics
wikipedia.org.Availabe from:https://en.wikipedia.org/wiki/ZF2001
www.precisionvaccinations.com . Available from:https://www.precisionvaccinations.com/vaccines/zf2001covid-19-vaccine
www.yalemedicine.org. Available from:https://www.yalemedicine.org/news/covid-19-vaccinecomparison
https://www.vizientinc.com/- /media/documents/sitecorepublishingdocuments/public/covid1 9_sidebyside_vaccinecompare.pdf.
Published
How to Cite
Issue
Section
Copyright (c) 2021 Deepak Bharati, Maria Alva, Simona D’souza, Sanya Lisboa, Sohail Sayyed
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Journal of Innovations in Pharmaceutical and Biological Sciences is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. Based on a work at 