Biophysicochemical changes in Nile tilapia, Oreochromis niloticus exposed to ZnSO4.7H2O and ZnCl2 metal toxicant


  • A K M Nur Alam Siddiki Department of Chemistry, Faculty of Science, University of Dhaka, Bangladesh
  • Mst Ummul Khair Department of Chemistry, Faculty of Science, University of Dhaka, Bangladesh
  • M. Niamul Naser Department of Zoology, Faculty of Biological Sciences, University of Dhaka, Bangladesh
  • Md. Abdus Salam Department of Chemistry, Faculty of Science, University of Dhaka, Bangladesh


During the present investigation, the LC50 values and lethal concentrations of ZnCl2 and ZnSO4.7H2O for Oreochromis niloticus were determined. The LC50 and lethal concentrations for each metal salts were computed by using Probit analysis method at 95% confidence interval. The 24, 48, 72-hr LC50 and lethal concentrations of Nile tilapia for zinc chloride were found to be 50.27 mg/L, 37.05 mg/L and 17.99 mg/L and for zinc sulphate were 68.73 mg/L, 51.71 mg/L and 44.62 mg/L in respective time intervals. The tolerance limits of fish for both zinc chloride and zinc sulphate varied significantly in terms of time and lethal concentrations. However, fish were significantly tolerant to zinc sulphate than that of zinc chloride. With the increase in metallic ion concentration of the water, the level conductivity and TDS (Total Dissolved Solids) increased, while that of dissolved oxygen decreased constantly. The reverse order of dissolved oxygen with concentration indicating that oxygen consumption by the fish decreases under metallic ion stress. The present study also assessed the proximate composition, including protein, lipid, moisture, dry ash, organic contents of Oreochromis niloticus exposed to ZnCl2 and ZnSO4.7H2O. This showed a significant decrease in protein, lipid, dry ash content and increase in moisture and organic content


LC50, acute toxicity test, biophysicochemical changes, zinc sulphate, zinc chloride, Oreochromis niloticus


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How to Cite

Siddiki, A. K. M. N. A., Mst Ummul Khair, M. Niamul Naser, and Md. Abdus Salam. “Biophysicochemical Changes in Nile Tilapia, Oreochromis Niloticus Exposed to ZnSO4.7H2O and ZnCl2 Metal Toxicant”. Journal of Innovations in Pharmaceutical and Biological Sciences, vol. 5, no. 2, Apr. 2018, pp. 113-8,



Research Article