Pharmacological evaluation of essential oils of Ocimum sanctum, Prunus persica and Zingiber officinale
DOI:
https://doi.org/10.56511/JIPBS.2016.v3.i02.pp07-11Abstract
The present study comprises pharmacological trials with the essential oils of Ocimum sanctum, Prunus persica and Zingiber officinale, which have been found to exhibit a fungitoxic effect on plant pathogenic fungi. Analysis of the blood and serum of albino rats fed with an oil-supplemented diet for sixty days did not reveal significant variations in the levels of hemoglobin, total blood glucose, protein, cholesterol, urea, serum glutamate oxaloacetate transaminase, serum glutamate pyruvate transaminase and alkaline phosphatase nor in differential leucocyte counts, in comparison to rats fed with a normal rat diet. These essential oils thus can be recommended as safe antifungal agents because the oils did not show any adverse alteration on different pharmacological parameters that have been observed in the present piece of work.
Keywords:
Ocimum sanctum, Prunus persica, Zingiber officinale, fungitoxicity, animal toxicity, pharmacology, essential oilsDownloads
References
French, RC. The bioregulatory action of flavour compounds on fungal spores and otherpropagules. Ann. Rev. Phytopathol 1985; 23:173-199.
Bruneton J. Pharmacognosy, Phytochemistry, Medicinal Plants: Essential oils. 2nd ed. Lavoisier Publishing, New York, 1999; 461-780.
Bakkali F, Averbeck S, Averbeck D, Idaomar M. Biological effects of essential oils – A review. Food and Chem. Tox. 2008; 46:446-475.
Franzios G, Mirotson M, Hatziapostolou E, Kral J, Scouras ZG, Mavragani TP. Insecticidal and genotoxic activities of mint essential oils. J. Agric. Food Chem. 1997; 45: 2690-2694.
Chang ST, Cheng SS. Antitermite activity of leaf essential oils and their constituents from Cinnamomum osmophloeum. J. Agric. Food. Chem. 2002; 50:1389-1392.
Anonymous. Mosquito repellents can have toxic effects, Reports of Times of India,: 1998; vol. CLXI, April, 17.
Tripathi, P., Dubey, N.K., Shukla, A.K. Use of some essential oils as post-harvest botanical fungicides in the management of grey mould of grapes caused by Botrytis cinerea, World J Microbiol Biotechnol 2008; 24:39-46.
Shaaya E, Kostjukovski M, Eilberg J, Sukprakarn, C. Plant oils a fumigant and contact insecticides for the control of stored product insects. J. stored Product research. 1997; 33:7-15
Varma J, Dubey NK. Efficacy of essential oils of Caesulia axillaris and Mentha arvensis against some storage pests causing biodeterioration of food commodities. International Journal of Food Microbiology. 2001; 68: 207-210
Tewari TN, Varma J, Dubey NK, Chansouria JPN, Ali Z. Pharmacological Evaluation of some bioactive plant products on albinorats. Hidustan Antibiot. Bull. 1998; 40: 38-41
Deans SG, Svoboda KP, Gundidza M, Brechany EY. Essential oil profiles of several temperate and tropical aromatic plants: their antimicrobial and antioxidant activities. Acta Horticulture 1992; 306: 229-232.
Piccaglia R, marotti M, Giovanelli E, Deans SG, Eaglesham E. Antibacterial and antioxidant properties of Mediterranean aromatic plants. Ind. Crops and Production 1993; 2: 47-50.
Carlton RR, Waterman PG, Gray AI, Deans SG. The antifungal activity of the leaf gland volatile oil of sweet gale (Myrica gale)(Myrtaceae).Chemoecology 1992; 3:55-59.
Published
How to Cite
Issue
Section
Copyright (c) 2016 Pramila Tripathi
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
Journal of Innovations in Pharmaceutical and Biological Sciences is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License. Based on a work at