@article{Sur_Avijit Hazra_2017, title={Preclinical evaluation of standardized anti-diabetic herbal formulation (ADC-05)}, volume={4}, url={https://jipbs.com/index.php/journal/article/view/219}, abstractNote={<p>ADC-05 a new formulation was prepared with nine standardized herbal extracts for anti-diabetic actions to find out the anti-diabetic potentialities in experimental animals as well as explore its potential mode of actions. ADC-05 exhibited rich in phenolics and showed DPPH antioxidant scavenging actions. Moreover, it showed a-amylase and α-glucosidase inhibition dose dependently. ADC-05 did not showed any signs of toxicity or mortality up to 2.0 g/kg per oral dose in mice. Oral administration of ADC-05 at the dose of 100 mg/kg and 200 mg/kg significantly declined the fasting blood sugar level within 2 h and 14 days consecutive treatments, similar to Glibenclamide in Streptozotocin induced hyperglycemic rats. In conclusion it may infer that new formulation ADC-05 has antidiabetic potentialities in rats.</p>}, number={2}, journal={Journal of Innovations in Pharmaceutical and Biological Sciences}, author={Sur, Tapas Kumar and Avijit Hazra}, year={2017}, month={Apr.}, pages={12–16} }