In vitro anti-Staphylococcus aureus activity of the methanol extract from Mitrephora thorelii Pierre’s branches and leaves in Lam Dong Province, Viet Nam
DOI:
https://doi.org/10.56511/JIPBS.2023.10101%20Abstract
We demonstrated that the methanol extract of Mitrephora thorelii Pierre's branches and leaves in Lam Dong, Vietnam is anti-Staphylococcus aureus strain (Sta1) of Phenikaa University, Hanoi, Viet Nam and Staphylococcus aureus ATCC 29213 strain (Sta2) from Thermo Fisher Scientific, USA. Invitro anti-Sta1 and Sta2 activity of the methanol extract of Mitrephora thorelii Pierre's branches and leaves were not significantly different. With a rise in extract content, the inhibitory zone's created diameter grew as well. The extract content of 100 mg/mL demonstrated the greatest antibacterial activity with a 25 mm inhibition zone diameter against Sta1 and 24 mm inhibition zone diameter against Sta2. Bacteria were not resistant to the extract at concentrations of 20; 80 and 100 mg/mL after 48, 72, and 96 hours. The lowest inhibitory concentration (MIC) was between 312.5 and 625 µg/mL. The minimum bactericidal concentration was found to be 1.25 mg/mL.
Keywords:
Antibacterial activity, Lam Dong, Mitrephora thorelii Pierre, Plants extract, Staphylococcus aureusDownloads
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