Antioxidant activity and α-glucosidase inhibition effect of water extract of Saurauia vulcani Korth leaves
DOI:
https://doi.org/10.56511/JIPBS.2018.v5.i03.pp47-51Abstract
Objective: Saurauia vulcani, Korth leaves contain several compounds such as polyphenols which have activity as the antioxidant. This plant is used traditionally in the treatment of diabetes mellitus and wound healing. Methods: Saurauia vulcani, Korth leaves powder was extracted by infundation method with water as solvent.This aim of this study was to determined the total content of phenol and flavonoid, antioxidant activity in DPPH method and activity of the α-glucosidase enzyme inhibition of water extract of Saurauia vulcani Korth leaf. Result: The results were showed that water extract has a total phenol content of 96.75± 0.02 mg/g GAE, a total flavonoid content of 39.50 ± 0.02 mg/g QE, antioxidant activity with DPPH method has an IC50 value 22.918 ± 1.32 µg/mL and the highest activity inhibition with IC50 value 75.56 ± 1.07μg/mL. Conclusion: Based on the results obtained that the water extract leaves of Saurauia vulcanihas a total phenol content, a total flavonoid content, antioxidant activity with DPPH method and inhibition of enzyme activity α-glucosidase giving synergistic effect
Keywords:
Antioxidant, vulcani korth, enzymeα-glucosidase, total phenol, total flavonoidDownloads
References
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